Kiadis Pharma is focused on cell-based immunotherapy products, as an adjunctive to a haploidentical hematopoietic stem cell transplantation (HSCT), for the treatment of blood cancers and inherited blood disorders. The Company’s product candidates have the potential to make allogeneic HSCT safer and more effective for patients.
Based on the positive results from the single dose Phase II trial with lead product ATIR101™ in patients with blood cancer, the Company submitted a Marketing Authorization Application (MAA) to the European Medicines Agency (EMA) in April 2017, for approval of ATIR101™ across the European Union as an adjunctive treatment in HSCT for malignant disease. In addition, Kiadis Pharma has received regulatory approval in various countries to start dosing patients in a Phase III trial with ATIR101™ that will be performed across Europe and North America. ATIR101™ has been granted Orphan Drug Designations both in the US and Europe.
The Company’s second product candidate, ATIR201™, will address beta thalassemia, an inherited blood disorder.
Kiadis Pharma was granted an Advanced Therapy Medicinal Product (ATMP) certificate for manufacturing quality and non-clinical data by the EMA.
The Company’s shares are listed on Euronext Amsterdam and Euronext Brussels.
We are looking for an experienced scientist for the Analytical Development and Quality Control department with an education in cell biology, immunology or related fields.
The ideal candidate has a PhD, hands-on experience with flow cytometry and is familiar with working under a GMP quality system. At least 3 years industry experience in assay development and assay validation is a must. Experience in working with cell-based assays as well as immunological techniques is required, as is proficiency with the statistical evaluation of assay performance using appropriate software, e.g. JMP, SPSS, Minitab or equivalent.
The (senior) scientist will guide efforts to optimize and validate cell-based assays for release purposes under GMP. This will require knowledge of analytical guidelines and relevant GMP regulations. He/she will be involved in method transfers, general laboratory qualifications like IOPQs, and will make use of statistical approaches such as DOEs to improve method robustness.
The candidate is a good team player with strong communication skills, is used to working in a matrix organization and is quality-driven.
You will be joining a team of scientists and technicians working on the development of personalized cell based-medicinal products. The lab team is located at the Amsterdam Science Park.
Kiadis Pharma is a public clinical stage biopharmaceutical company focused on research, development and future commercialization of innovative cell-based immunotherapy products that provide for a safer and more efficacious treatment of blood cancers and inherited blood disorders, improving survival and quality of life and addressing significant unmet medical needs.
- PhD in immunology, cell biology or equivalent.
- >3 years experience in the biotech or pharmaceutical industry.
- Expertise in cell-based assay development and validation under GMP.
- Experience with the evaluation of assay performance using statistical software.
- Hands-on experience with flow cytometry is a pre.
For further information, please contact Jeroen Elderhorst, HR Manager, by phone at +31 (0)20 3140 250. You can e-mail your motivation letter and resume to firstname.lastname@example.org.